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BNIP3 Products

BNIP3 and its closely related functional homolog, BNIP3L, are proapoptotic mitochondrial proteins that are regulated by HIF-1 alpha. Each of these contains a single Bcl-2 homology 3 (BH3) domain and a C-terminal transmembrane domain required for mitochondrial localization, homodimerization, and regulation of its proapoptotic function. The mechanism of BNIP3-mediated apoptosis is independent of caspase activation and cytochrome c release.

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162 results for "BNIP3" in Products

162 results for "BNIP3" in Products

BNIP3 Products

BNIP3 and its closely related functional homolog, BNIP3L, are proapoptotic mitochondrial proteins that are regulated by HIF-1 alpha. Each of these contains a single Bcl-2 homology 3 (BH3) domain and a C-terminal transmembrane domain required for mitochondrial localization, homodimerization, and regulation of its proapoptotic function. The mechanism of BNIP3-mediated apoptosis is independent of caspase activation and cytochrome c release.

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Recombinant Monoclonal Antibody.

Recombinant Monoclonal Antibody

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