BMP-2 Products
BMP-2 (Bone morphogenetic protein 2) is a TGF-beta superfamily cytokine that plays a dominant role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 forms disulfide linked homodimers and heterodimers with BMP-7. BMP-2 signals through heterodimeric complexes of type I receptors (ActiRI, BMPR-IA, or BMPR-IB) and type II receptors (BMP RII or ActRIIB).
It induces chondrocyte proliferation, endochondral bone formation, longitudinal bone growth, and bone and cartilage repair. BMP-2/BMP-7 heterodimers are significantly more potent than BMP-2 homodimers at inducing bone formation in vivo. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility.
Products:
229 results for "BMP-2" in Products
229 results for "BMP-2" in Products
BMP-2 Products
BMP-2 (Bone morphogenetic protein 2) is a TGF-beta superfamily cytokine that plays a dominant role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 forms disulfide linked homodimers and heterodimers with BMP-7. BMP-2 signals through heterodimeric complexes of type I receptors (ActiRI, BMPR-IA, or BMPR-IB) and type II receptors (BMP RII or ActRIIB).
It induces chondrocyte proliferation, endochondral bone formation, longitudinal bone growth, and bone and cartilage repair. BMP-2/BMP-7 heterodimers are significantly more potent than BMP-2 homodimers at inducing bone formation in vivo. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility.
Products:
| Sensitivity: | 29 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Bone Extracts) |
| Reactivity: | Human, Mouse, Rat, Canine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
Simple Plex Human BMP-2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
| Applications: | Simple Plex |
| Assay Range: | 46.9 - 3,000 pg/mL |
| Applications: | ELISA |
| Source: | E. coli |
| Accession #: | P12643 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #100221 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #100230 |
| Applications: | WB, Neut |
| Source: | CHO |
| Accession #: | P12643 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | P12643.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | NP_001191 (BMP-2) & NP_001710 (BMP-7) |
| Applications: | BA |
Control for use with Human BMP-2 Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #253717 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #65529 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
| Source: | E. coli |
| Accession #: | P12643 (BMP-2) & P22004 (BMP-6) |
| Applications: | BA |
For use with catalog numbers DBP200, SBP200, PDBP200
| Applications: | Ctrl |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #100230 |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #100221 |
| Applications: | WB, ELISA(Cap), ELISA(Det) |
| Reactivity: | Zebrafish |
| Details: | Mouse IgG1 Monoclonal Clone #208301 |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #100221 |
| Applications: | WB, ELISA(Cap), ELISA(Det) |