beta-III Tubulin: Proteins and Enzymes

Tubulin is the major component of microtubules, essential cell cytoskeleton proteins involved in mitosis, cytokinesis and transport of vesicles and organelles. Tubulin is a dimer composed of one alpha and one beta tubulin molecule, which assemble as microtubules in a GTP-dependent manner. The beta-Tubulin molecule exerts GTPase activity to hydrolyze to GDP, effectively governing microtubule formation. Tubulin bound to GTP is prone to form microtubules whereas GDP-bound tubulin molecules in ...