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4 results for "B7-1/CD80" in Products

B7-1/CD80 Products

B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20 - 100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.

Clone 2D10.4 was used by HLDA to establish CD designation.

Reactivity:
Human
Details:
Mouse IgG1 kappa Monoclonal Clone #2D10.4
Applications:
Flow
Novus Antibodies
Reactivity:
Human, Mouse, Feline
Details:
Armenian Hamster IgG Monoclonal Clone #16-10A1
Applications:
Flow
Novus Antibodies
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