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11 results for "Adrenergic alpha-2 Receptor Antagonists" in Products

Adrenergic alpha-2 Receptor Antagonists Products

Adrenergic α2 receptors (α2-adrenoceptors) are members of the adrenergic receptor group of G-protein-coupled receptors that also includes α1A, α1B, α1D, β1, β2 and β3. Adrenergic α2 receptors are divided into three subtypes: α2A, α2B and α2C, which are widely distributed in both the CNS and periphery. α2-adrenoceptors play a role in the modulation of neurotransmission, smooth muscle contraction and thermoregulation. A fourth pharmacological subtype, α2D, has been identified in the rat which is thought to be a species ortholog of the human α2A subtype.

Adrenergic α receptor antagonist; antihypertensive

α1 and α2B antagonist; also MT3 antagonist

Selective α2 antagonist

Selective α2 antagonist

Potent and selective α2C antagonist

Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant

Selective α2A antagonist

Potent and selective α2 antagonist

Potent and selective adrenergic α2B antagonist

Potent, selective α2D antagonist

Highly selective α2B antagonist

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