Yohimbine hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 1127

Selective α2 antagonist
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Key Product Details

Description

Selective α2 antagonist

View all Adrenergic alpha-2 Receptor Antagonists »

Product Description

Yohimbine hydrochloride is a α2-adrenoceptor antagonist (pKi values are 8.52, 8.00 and 9.17 for human α2A, α2B and α2C receptors respectively).

Diastereomer also available.

Product Specifications

Molecular Weight

390.91

Formula

C21H26N2O3.HCl

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

17α-Hydroxyyohimban-16α-carboxylic acid methyl ester hydrochloride

CAS Number

65-19-0

PubChem ID

6169

InChI Key

PIPZGJSEDRMUAW-VJDCAHTMSA-N

SMILES

[H][C@]12C4=C(C(C=CC=C5)=C5N4)CCN1C[C@@]3([H])[C@]([C@@H]([C@@](OC)=O)[C@@H](O)CC3)([H])C2.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 7.82 20 with gentle warming

Preparing Stock Solutions for Yohimbine hydrochloride

The following data is based on the product molecular weight 390.91

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 12.79 mL 63.95 mL 127.91 mL
1 mM 2.56 mL 12.79 mL 25.58 mL
2 mM 1.28 mL 6.40 mL 12.79 mL
10 mM 0.26 mL 1.28 mL 2.56 mL

Calculators

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Yohimbine hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Yohimbine hydrochloride

For research use only

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