5-Lipoxygenase: Small Molecules and Peptides
5-Lipoxygenase (5-LO) is a nonheme iron dioxygenase that converts nuclear membrane arachidonic acid into leukotriene A4 (LTA4). 5-LO is found in leukocytes and generally exists in the cytoplasm but may translocate into the nucleus when activated. In the nucleus, its enzyme products impact gene expression; in the cytosol, its products are secreted and contribute to inflammation.
2 results for "5-Lipoxygenase Small Molecules and Peptides" in Products
2 results for "5-Lipoxygenase Small Molecules and Peptides" in Products
5-Lipoxygenase: Small Molecules and Peptides
5-Lipoxygenase (5-LO) is a nonheme iron dioxygenase that converts nuclear membrane arachidonic acid into leukotriene A4 (LTA4). 5-LO is found in leukocytes and generally exists in the cytoplasm but may translocate into the nucleus when activated. In the nucleus, its enzyme products impact gene expression; in the cytosol, its products are secreted and contribute to inflammation.
Selective 15-lipoxygenase inhibitor
| Chemical Name: | 6,11-Dihydro[1]benzothiopyrano[4,3-b]indole |
| Purity: | ≥98% (HPLC) |
5-LOX inhibitor; orally bioavailable
| Alternate Names: | ICI D2138 |
| Chemical Name: | N-(1-Benzo[b]thien-2-ylethyl)-N-hydroxyurea |
| Purity: | ≥98% (HPLC) |
