Recombinant Protein Development
Your Protein, Our Expertise.
We understand that drug and diagnostic development can be challenging. From target identification to timeline and budgetary constraints, the last thing any scientist wants to consider is the intricacies of protein development. Our seasoned experts are committed to addressing your specific needs. Leave the guesswork out of protein development and partner with Bio-Techne to meet your project goals.
Custom Protein Production by the Numbers
40 Years of Experience
40 Years of Experience
R&D Systems scientists have been manufacturing proteins since 1985 when we became the first company in the world to commercially produce TGF-beta 1.
More than 6,000 Bioactive Proteins Developed
More than 6,000 Bioactive Proteins Developed
Unparalleled experience ranging from cytokines, growth factors to enzymes and viral targets.
When proteins produced by Bio-Techne were compare in side-by-side bioassays with competitors, over half of the 43 tested exhibited 1.5-gold or higher bioactivity.
Highly Cited
Highly Cited
2023 Bioz All Star™ – Cytokines | Awarded to the supplier that has earned the highest average Bioz Stars score within the cytokine product category.
In a survey of more than 800 publications, 36% cited use of R&D Systems proteins from Bio‑Techne, greater than any other single manufacturer.
End-to-End Protein Development Solutions
Design
All successful projects start with a good plan. We utilize a variety of tools including multiple promoters, tags, and expression hosts. Push the design boundaries with the latest in protein computational modeling from codon optimization to designer proteins with mutational prediction.
Development
A good plan still requires good execution. We’ve developed a host of in-house proprietary transfection, cell culture, and purification techniques to tackle the toughest proteins. Talk to one of our specialists about our full scale approach that utilizes high throughput approaches to test a variety of parameters.
Scalability
We understand that timelines and plans can change quickly, necessitating need for flexibility. We’re set up to quickly change batch sizes or move to full scale production with our dedicated manufacturing teams. Stuck with a poor scaling reagent? Kick it back to develop and optimize parameters without compromising current supply.
Quality Systems
Bio-Techne is proud to have robust quality systems that provide our customers peace of mind. Whether it’s batch-to-batch testing or DMF submissions, we have you covered. R&D Systems, a Bio-Techne brand, is located in Minneapolis, MN. Our facilities are specifically designed to produce high quality reagents.
Our 4 Pillar Protein Production Philosophy
Bioactivity
Not all proteins are made equal! Using poor performing proteins could waste precious research budget. R&D Systems believes in developing proteins with correct conformational folding to ensure our customers research conclusions and experiments are successful.
Purity
Be confident that the results obtained in your experiments are not due to contaminants. The majority of our proteins have >95% purity and have guaranteed industry-leading endotoxin level of ≤0.1 EU/µg (established by LAL assay).
Stability
We constantly monitor the condition of our proteins to check for long term performance. Our proteins are shipped lyophilized or in specially optimized formulations, so each recombinant protein reaches you in perfect conditions.
Consistency
Our customers can expect reliability of their proteins. We employ rigorous QC and production standards. Each new lot is compared to the previous the strict acceptance criteria.