DMG-PEG 2000
Tocris Bioscience, part of Bio-Techne | Catalog # 7944
PEGylated myristoyl diglyceride; commonly used in the formation of lipid nanoparticles (LNPs)
Key Product Details
Description
PEGylated myristoyl diglyceride; commonly used in the formation of lipid nanoparticles (LNPs)
Product Description
DMG-PEG 2000 is a PEGylated myristoyl diglyceride consisting of one unbranched PEG 2000 chain and two saturated fatty acid chains (C14:0) covalently attached to a glycerol. DMG-PEG 2000 is commonly used in the formation of lipid nanoparticles (LNPs) and liposomes to prevent serum protein adsorption, nanoparticle aggregation and increase in vivo circulation time. DMG-PEG 2000 is a component of LNPs which can be used for delivery of RNA-based vaccines or mRNA therapeutics.For more information on how to prepare MC3 lipid nanoparticles for RNA delivery, please see our protocol.
For a fully formulate LNP containing DLin-MC3-DMA and a luciferase mRNA reporter, see MC3 LNP Luciferase (Cat. No. 8889).
Product Specifications
Formula
(C2H4O)nC32H62O5
Storage
Store at -20°C
Purity
≥90% (HPLC)
Chemical Name
1,2-Dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000
CAS Number
160743-62-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 10mg/ml in chloroform and to 10mg/ml in Ethanol |
Calculators
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Zhang Functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing. Sci.Adv. 2020 PMID: 32937374
- Cheng Dendrimer-based lipid nanoparticles deliver therapeutic FAH mRNA to normalize liver function and extend survival in a mouse model of hepatorenal tyrosinemia type I. Adv.Mater. 2018 PMID: 30368954
Product Specific Notices for DMG-PEG 2000
For research use only
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