MC3 LNP Luciferase
Tocris Bioscience, part of Bio-Techne | Catalog # 8889
Dlin-MC3 containing LNP for in vitro and in vivo delivery of luciferase mRNA
Discontinued Product
8889 has been discontinued.
View all Lipid Nanoparticle Components products.
Key Product Details
Description
Dlin-MC3 containing LNP for in vitro and in vivo delivery of luciferase mRNA
Product Description
MC3 LNP Luciferase is a fully formulated lipid nanoparticle (LNP) composed of DLin-MC3-DMA (Cat. No. 7946), DSPC (Cat. No. 7943), Cholesterol (Cat. No. 7945), DMG-PEG 2000 (Cat. No. 7944) with the molar ratio 50:10:38.5:1.5 providing a convenient, ready to use, benchmark LNP formulation. Contains a reporter luciferase mRNA for in vitro and in vivo bioluminescence detection when used with D-luciferin (Cat. No. 5427).For more information on how to prepare MC3 lipid nanoparticles for RNA delivery, please see our protocol.
Do not use a vortex to resuspend LNPs as this can disrupt the lipid membrane and damage particle integrity.
Product Specifications
Storage
Store at -80°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble in TBS buffer solution (10% sucrose, pH 7.5). Supplied in 200 µL aliquots, 0.05 µg/µL RNA concentration |
Calculators
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Brown Safe and effective in vivo delivery of DNA and RNA using proteolipid vehicles. Cell 2024 PMID: 39260374
Product Specific Notices for MC3 LNP Luciferase
For research use only
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