WKYMVM

Name: WKYMVM
Brand: Tocris Bioscience
SKU: 1799

Tocris Bioscience, part of Bio-Techne | Catalog # 1799

Citations (9)

COA / SDS

Selective FPR2 and FPR3 receptor agonist

Discontinued Product

1799 has been discontinued. View all Formyl Peptide Receptor Agonists products.

Key Product Details

Description:	Selective FPR2 and FPR3 receptor agonist
Alternative Names:	W-peptide
Molecular Weight:	856.11

View Full Technical Details for WKYMVM

Technical Data
Citations

Biological Activity for WKYMVM

WKYMVM is a selective agonist for the formyl peptide receptors FPR2 and FPR3, expressed on immune cells. EC₅₀ values for induction of calcium mobilization in FPR2-HL-60 cells and FPR3-HL-60 cells are 2 and 80 nM respectively.

Technical Data for WKYMVM

M. Wt	856.11
Formula	C₄₁H₆₁N₉O₇S₂
Single Letter Sequence	WKYMVM (Modifications: Met-6 = C-terminal amide)
Storage	Desiccate at -20°C
CAS Number	187986-11-4
PubChem ID	68661247
InChi Key	FMBGOORJEKQQLG-LXOXETEGSA-N
Smiles	[H]N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for WKYMVM

References are publications that support the biological activity of the product.

Christophe The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH₂ specifically activates neutrophils through FPRL1/Lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. J.Biol.Chem. 2001 PMID: 11285256
Christophe Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1 /LXA4R, is not affected by lipoxin. Scand.J.Immunol. 2002 PMID: 12410796
Baek Identification of the peptides that stimulate the phosphoinositide hydrolysis in lymphocyte cell lines from peptide libraries. J.Biol.Chem. 1996 PMID: 8626507

WKYMVM

Tocris Bioscience, part of Bio-Techne | Catalog # 1799

Key Product Details

Biological Activity for WKYMVM

Technical Data for WKYMVM

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for WKYMVM

Product Documents for WKYMVM

COA

Certificate of Analysis

SDS

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