WKYMVM
Tocris Bioscience, part of Bio-Techne | Catalog # 1799
Selective FPR2 and FPR3 receptor agonist
Discontinued Product
1799 has been discontinued.
View all Formyl Peptide Receptor Agonists products.
Key Product Details
Description
Selective FPR2 and FPR3 receptor agonist
Alternative Names
W-peptide
Product Description
WKYMVM is a selective agonist for the formyl peptide receptors FPR2 and FPR3, expressed on immune cells. EC50 values for induction of calcium mobilization in FPR2-HL-60 cells and FPR3-HL-60 cells are 2 and 80 nM respectively.Product Specifications
Molecular Weight
856.11
Formula
C41H61N9O7S2
Storage
Desiccate at -20°C
CAS Number
187986-11-4
PubChem ID
68661247
InChI Key
FMBGOORJEKQQLG-LXOXETEGSA-N
SMILES
[H]N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 0.6mg/ml in water |
Calculators
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Background References
References are publications that support the biological activity of the product.
- Christophe The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/Lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. J.Biol.Chem. 2001 PMID: 11285256
- Christophe Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1 /LXA4R, is not affected by lipoxin. Scand.J.Immunol. 2002 PMID: 12410796
- Baek Identification of the peptides that stimulate the phosphoinositide hydrolysis in lymphocyte cell lines from peptide libraries. J.Biol.Chem. 1996 PMID: 8626507
Product Specific Notices for WKYMVM
For research use only
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