TC-G 1001
Tocris Bioscience, part of Bio-Techne | Catalog # 4879
GPR35 agonist; more potent than zaprinast (Cat. No. 0947)
Key Product Details
Description
GPR35 agonist; more potent than zaprinast (Cat. No. 0947)
Product Description
TC-G 1001 is a GPR35 agonist (pEC50 values are 7.59 and 8.36 for β-arrestin and Gαq-i5 Ca2+ assays respectively). Displays 1000-fold greater potency at human GPR35 receptors relative to mouse and rat GPR35 orthologs in an IP1 accumulation assay. More potent than zaprinast (Cat. No. 0947).Product Specifications
Molecular Weight
342.34
Formula
C17H11FN2O3S
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
4-[[2-[(2-Fluorophenyl)amino]-4-oxo-5(4H)-thiazolylidene]methyl]benzoic acid
CAS Number
494191-73-0
PubChem ID
5766343
InChI Key
SYCKPHBALHXMIR-ZROIWOOFSA-N
SMILES
O=C1N=C(NC3=CC=CC=C3F)S/C1=C\C2=CC=C(C(O)=O)C=C2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 3.42 | 10 |
Preparing Stock Solutions
for TC-G 1001
The following data is based on the product molecular weight 342.34
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.21 mL | 146.05 mL | 292.11 mL |
| 0.5 mM | 5.84 mL | 29.21 mL | 58.42 mL |
| 1 mM | 2.92 mL | 14.61 mL | 29.21 mL |
| 5 mM | 0.58 mL | 2.92 mL | 5.84 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Neetoo-Isseljee High-throughput identification and characterization of novel, species-selective GPR35 agonists. J.Pharmacol.Exp.Ther. 2013 PMID: 23262279
Product Specific Notices for TC-G 1001
For research use only
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