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S 24795

Tocris Bioscience, part of Bio-Techne | Catalog # 3518

α7 nAChR partial agonist
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3518/10
3518/50

Key Product Details

Description

α7 nAChR partial agonist

Product Description

S 24795 is a partial agonist of α7 nAChR. Improves mnemonic function in aged mice for the treatment of aging-related memory disturbances. Displays more efficient memory-enhancing effects than memantine (Cat. No. 0773) in Alzheimer's disease mouse models.

Product Specifications

Molecular Weight

418.07

Formula

C14H13BrINO

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

2-[2-(4-Bromophenyl)-2-oxoethyl]-1-methylpyridinium iodide

CAS Number

304679-75-2

PubChem ID

9888248

InChI Key

LERUHBBUGAOYOD-UHFFFAOYSA-M

SMILES

BrC1=CC=C(C(CC2=[N+](C)C=CC=C2)=O)C=C1.[I-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 4.18 10 with gentle warming
DMSO 41.81 100

Preparing Stock Solutions for S 24795

The following data is based on the product molecular weight 418.07

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.39 mL 11.96 mL 23.92 mL
5 mM 0.48 mL 2.39 mL 4.78 mL
10 mM 0.24 mL 1.20 mL 2.39 mL
50 mM 0.05 mL 0.24 mL 0.48 mL

Calculators

Molarity Calculator

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Reconstitution Calculator

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Product Documents for S 24795

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for S 24795

For research use only

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