O-1918
Tocris Bioscience, part of Bio-Techne | Catalog # 2288
Silent antagonist for putative abnormal-CBD (Cat. No. 1297) receptor
Discontinued Product
2288 has been discontinued.
View all Additional Cannabinoid-related Compounds products.
Key Product Details
Description
Silent antagonist for putative abnormal-CBD (Cat. No. 1297) receptor
Product Description
O-1918 is a selective, silent antagonist of a putative endothelial anandamide receptor distinct from CB1 or CB2 receptors. Inhibits vasodilation and cell migration induced by abnormal-cannabidiol (abn-CBD; Cat. No. 1297).Licensing Information
Sold under license from the NIH, US patent 60/312,674Product Specifications
Molecular Weight
286.41
Formula
C19H26O2
Storage
Store at -20°C
Purity
≥97% (HPLC)
Chemical Name
1,3-Dimethoxy-5-methyl-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]benzene
CAS Number
536697-79-7
PubChem ID
40469923
InChI Key
ICHJMVMWPKLUKT-JKSUJKDBSA-N
SMILES
COC1=CC(C)=CC(OC)=C1[C@@H]1C=C(C)CC[C@H]1C(C)=C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 28.64 | 100 | |
| Ethanol | 28.64 | 100 |
Preparing Stock Solutions
for O-1918
The following data is based on the product molecular weight 286.41
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.49 mL | 17.46 mL | 34.91 mL |
| 5 mM | 0.70 mL | 3.49 mL | 6.98 mL |
| 10 mM | 0.35 mL | 1.75 mL | 3.49 mL |
| 50 mM | 0.07 mL | 0.35 mL | 0.70 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Mo Atypical cannabinoid stimulates endothelial cell migration via a Gi/Go coupled receptor distinct from CB1, CB2 or EDG-1. Eur.J.Pharmacol. 2004 PMID: 15063151
- Hoi and Hiley Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor. Br.J.Pharmacol. 2006 PMID: 16415907
- Offertáler Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor. Mol.Pharmacol. 2003 PMID: 12606780
Product Specific Notices for O-1918
For research use only
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