Abn-CBD is a neurobehaviorally inactive cannabinoid that acts as a selective agonist for GPR55 (EC₅₀ values are 2.5, >30 and >30 μM at GPR55, CB₁ and CB₂ receptors respectively). Increases phosphorylation of protein kinases in, and migration of, human umbilical vein endothelial cells.

Product Specifications

Molecular Weight

314.47

Formula

C₂₁H₃₀O₂

Storage

Desiccate at -20°C

Purity

≥97% (HPLC)

Chemical Name

4-[(1R,6R)-3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol

CAS Number

22972-55-0

PubChem ID

89949

InChI Key

YWEZXUNAYVCODW-RBUKOAKNSA-N

SMILES

C=[C@](C)[C@@H]1CCC(C)=C[C@H]1[C@]2=C(O)C=C(O)C=C2CCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble in methyl acetate (supplied pre-dissolved - 5mg/ml)

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Background References

References are publications that support the biological activity of the product.

Ryberg The orphan receptor GPR55 is a novel cannabinoid receptor. Br.J.Pharmacol. 2007 PMID: 17876302
Jarai Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proc.Natl.Acad.Sci.U.S.A. 1999 PMID: 10570211
Mo Atypical cannabinoid stimulates endothelial cell migration via a G_i/G_o-coupled receptor distinct from CB₁, CB₂ or EDG-1. Eur.J.Pharmacol. 2004 PMID: 15063151
Ho and Hiley Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery. Br.J.Pharmacol. 2003 PMID: 12711633

Abn-CBD

Tocris Bioscience, part of Bio-Techne | Catalog # 1297

Key Product Details

Description

Alternative Names

View all GPR55 Receptor Agonists »

Product Description