Methylergometrine maleate
Tocris Bioscience, part of Bio-Techne | Catalog # 0549
Active metabolite of methysergide (Cat. No. 1064)
Key Product Details
Description
Active metabolite of methysergide (Cat. No. 1064)
Alternative Names
Methylergonovine maleate
Product Description
Methylergometrine maleate is an active metabolite of methysergide (Cat. No. 1064); uterotonic agent and oxytocic.Product Specifications
Molecular Weight
455.51
Formula
C20H25N3O2.C4H4O4
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
[8β(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-6-methylergoline-8-carboxamide maleate
CAS Number
57432-61-8
PubChem ID
5281072
InChI Key
NOFOWWRHEPHDCY-DAUURJMHSA-N
SMILES
OC(=O)\C=C/C(O)=O.[H][C@](CC)(CO)NC(=O)[C@@]1([H])CN(C)[C@]2([H])CC3=CNC4=C3C(=CC=C4)C2=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 25 |
Preparing Stock Solutions
for Methylergometrine maleate
The following data is based on the product molecular weight 455.51
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.25 mM | 8.78 mL | 43.91 mL | 87.81 mL |
| 1.25 mM | 1.76 mL | 8.78 mL | 17.56 mL |
| 2.5 mM | 0.88 mL | 4.39 mL | 8.78 mL |
| 12.5 mM | 0.18 mL | 0.88 mL | 1.76 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Muller-Schweinitzer and Tapparelli Methylergometrine, an active metabolite of methysergide. Cephalalgia 1986 PMID: 3698092
- Pertz 5-Hydroxytryptamine (5-HT) contracts the guinea-pig isolated iliac artery via 5-HT1-like and 5-HT2 receptors. Naunyn Schmiedebergs Arch.Pharmacol. 1993 PMID: 8133899
- MacLennan and Martin Actions of non-peptide ergot alkaloids at 5-HT1-like and 5-HT2 receptors mediating vascular smooth muscle contraction. Naunyn Schmiedebergs Arch.Pharmacol. 1990 PMID: 2234096
Product Specific Notices for Methylergometrine maleate
For research use only
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