Methysergide maleate
Tocris Bioscience, part of Bio-Techne | Catalog # 1064
5-HT1/5-HT2 antagonist
Key Product Details
Description
5-HT1/5-HT2 antagonist
Product Description
Methysergide maleate is a mixed 5-HT1/5-HT2 receptor antagonist.Product Specifications
Molecular Weight
469.54
Formula
C21H27N3O2.C4H4O4
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
[8β(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-1,6-dimethylergoline-8-carboxamide maleate
CAS Number
129-49-7
PubChem ID
5281073
InChI Key
LWYXFDXUMVEZKS-ZVFOLQIPSA-N
SMILES
OC(=O)\C=C/C(O)=O.[H][C@@]12CC3=CN(C)C4=CC=CC(=C34)C1=C[C@H](CN2C)C(=O)N[C@@H](CC)CO
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 4.7 | 10 with gentle warming |
Preparing Stock Solutions
for Methysergide maleate
The following data is based on the product molecular weight 469.54
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.30 mL | 106.49 mL | 212.97 mL |
| 0.5 mM | 4.26 mL | 21.30 mL | 42.59 mL |
| 1 mM | 2.13 mL | 10.65 mL | 21.30 mL |
| 5 mM | 0.43 mL | 2.13 mL | 4.26 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Hoyer VII. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol.Rev. 1994 PMID: 7938165
Product Specific Notices for Methysergide maleate
For research use only
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