HX 630

Name: HX 630
Brand: Tocris Bioscience
SKU: 3913

Tocris Bioscience, part of Bio-Techne | Catalog # 3913

COA / SDS

RXR synergist

Discontinued Product

3913 has been discontinued. View all Additional Retinoid X Receptor Compounds products.

Key Product Details

Description:	RXR synergist
Chemical Name:	4-(7,8,9,10-Tetrahydro-7,7,10,10-tetramethylbenzo[b]naphtho[2,3-f][1,4]thiazepin-12-yl-benzoic acid
Purity:	≥98% (HPLC)
Molecular Weight:	441.58

View Full Technical Details for HX 630

Technical Data
Citations

Biological Activity for HX 630

HX 630 is a RXR agonist. Acts as a retinoid synergist; enhances the potency of AM 80 (Cat. No. 3507) in a HL-60 cell differentiation assay.

Licensing Information

Sold under licence.

Technical Data for HX 630

M. Wt	441.58
Formula	C₂₈H₂₇NO₂S
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	188844-52-2
PubChem ID	9889522
InChi Key	PFGCWQPTOKPRRK-UHFFFAOYSA-N
Smiles	CC3(C)CCC(C)(C)C(C3=C4)=CC2=C4C(C5=CC=C(C(O)=O)C=C5)=NC1=CC=CC=C1S2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for HX 630

References are publications that support the biological activity of the product.

Ohashi Effect of natural and synthetic retinoids on the proliferation and differentiation of three canine melanoma cell lines. J.Vet.Med.Sci. 2002 PMID: 11913557
Ishida Clinically potential subclasses of retinoid synergists revealed by gene expression profiling. Mol.Cancer Ther. 2003 PMID: 12533672
Umemiya Regulation of retinoidal actions by diazepinylbenzoic acids. Retinoid synergists which activate the RXR-RAR heterodimers. J.Med.Chem. 1997 PMID: 9435893