(±)-AC 7954 hydrochloride

Name: (±)-AC 7954 hydrochloride
Brand: Tocris Bioscience
SKU: 2484

Tocris Bioscience, part of Bio-Techne | Catalog # 2484

COA / SDS

Non-peptide UT receptor agonist

Discontinued Product

2484 has been discontinued. View all Urotensin-II Receptor Agonists products.

Key Product Details

Description:	Non-peptide UT receptor agonist
Chemical Name:	(±)-3-(4-Chlorophenyl)-3-[2-(dimethylamino)ethyl]-3,4-dihydro-1H-2-benzopyran-1-one hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	366.28

View Full Technical Details for (±)-AC 7954 hydrochloride

Technical Data
Citations

Biological Activity for (±)-AC 7954 hydrochloride

(±)-AC 7954 hydrochloride is a highly selective, non-peptide urotensin-II (UT) receptor agonist that displays potent activity at human and rat UT receptors (pEC₅₀ values are 6.5 and 6.7 respectively).

Technical Data for (±)-AC 7954 hydrochloride

M. Wt	366.28
Formula	C₁₉H₂₀ClNO₂.HCl
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	477313-09-0
PubChem ID	9907171
InChi Key	AJPGLOWFIBOGMH-UHFFFAOYSA-N
Smiles	Cl.CN(C)CCC1(CC2=CC=CC=C2C(=O)O1)C1=CC=C(Cl)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for (±)-AC 7954 hydrochloride

References are publications that support the biological activity of the product.

Lavecchia Architecture of the human urotensin II receptor: comparison of the binding domains of peptide and non-peptide urotensin II agonists. J.Med.Chem. 2005 PMID: 15801838
Lehmann Novel potent and efficacious nonpeptidic urotensin II receptor agonists. J.Med.Chem. 2006 PMID: 16570919
Croston Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2-(dimethylamino)ethyl)isochroman-1-one (AC-7954). J.Med.Chem. 2002 PMID: 12408704

(±)-AC 7954 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 2484

Key Product Details

Biological Activity for (±)-AC 7954 hydrochloride

Technical Data for (±)-AC 7954 hydrochloride

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for (±)-AC 7954 hydrochloride

Product Documents for (±)-AC 7954 hydrochloride

COA

Certificate of Analysis

SDS

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