Dibutyryl-cAMP, sodium salt New

Name: Dibutyryl-cAMP, sodium salt
Brand: Tocris Bioscience
SKU: TB1141-RMU

Tocris Bioscience, part of Bio-Techne | Catalog # TB1141-RMU

COA / SDS

Dibutyryl-cAMP, sodium salt synthesized to Ancillary Material Grade

Key Product Details

Description:	Dibutyryl-cAMP, sodium salt synthesized to Ancillary Material Grade
Alternative Names:	Bucladesine sodium
Chemical Name:	N⁶,O^2'-Dibutyryladenosine 3',5'-cyclic monophosphate sodium salt
Purity:	≥98%
Molecular Weight:	491.37

View Full Technical Details for Dibutyryl-cAMP, sodium salt

Technical Data
Citations

Biological Activity for Dibutyryl-cAMP, sodium salt

Dibutyryl-cAMP sodium salt is a cell-permeable analog of cAMP that activates cAMP-dependent protein kinases and is a phosphodiesterase inhibitor. Combined with other reagents, dibutyryl-cAMP promotes differentiation of neural stem/progenitor cells (NSPCs) and other cell lines (see our protocol below) and increases survival rates of NSPCs and differentiation into neurons in vivo. Promotes neurite outgrowth in cell cultures. Dibutyryl-cAMP has anti-inflammatory activity and is used to promote wound healing. Choline acetyltransferase and vesicular acetylcholine transporter mRNA are increased in cells treated with dibutyryl-cAMP.

For more information about how Dibutyryl-cAMP, sodium salt may be used, see our protocol: Generating Midbrain Dopaminergic Neurons from hPSCs

This product is Bio-Techne's ancillary Material Grade version of Dibutyryl-cAMP sodium salt (Cat. No. 1141). Suitable for use in research and further manufacturing of cell therapies. Find out more about our Ancillary Material Grade product range.

Technical Data for Dibutyryl-cAMP, sodium salt

M. Wt	491.37
Formula	C₁₈H₂₃N₅NaO₈P
Storage	Store at -20°C(±5°C)
Purity	≥98%
CAS Number	16980-89-5
PubChem ID	23663967
InChi Key	KRBZRVBLIUDQNG-JBVYASIDSA-M
Smiles	[H][C@]([C@]1([H])[C@H]2OC(CCC)=O)(COP(O1)([O-])=O)O[C@H]2N3C=NC4=C3N=CN=C4NC(CCC)=O.[Na+]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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Product Documents for Dibutyryl-cAMP, sodium salt

COA

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service.