7-Hydroxy-DPAT hydrobromide
Tocris Bioscience, part of Bio-Techne | Catalog # 0706
Dopamine agonist (D3 ≥ D2 < > D4)
Discontinued Product
0706 has been discontinued.
View all Dopamine D3 Receptor Agonists products.
Key Product Details
Description
Dopamine agonist (D3 ≥ D2 < > D4)
Product Description
7-Hydroxy-DPAT hydrobromide is a D3 dopamine receptor agonist (Ki values are ~ 1, 10, 650 and ~ 5000 nM for D3, D2, D4 and D1 receptors respectively).8-Hydroxy Isomer also available.
Product Specifications
Molecular Weight
328.28
Formula
C16H25NO.HBr
Storage
Desiccate at +4°C
Purity
≥99% (HPLC)
Chemical Name
(±)-7-Hydroxy-2-dipropylaminotetralin hydrobromide
CAS Number
76135-30-3
PubChem ID
11957566
InChI Key
ODNDMTWHRYECKX-UHFFFAOYSA-N
SMILES
Br.CCCN(CCC)C1CCC2=CC=C(O)C=C2C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 32.83 | 100 |
Preparing Stock Solutions
for 7-Hydroxy-DPAT hydrobromide
The following data is based on the product molecular weight 328.28
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.05 mL | 15.23 mL | 30.46 mL |
| 5 mM | 0.61 mL | 3.05 mL | 6.09 mL |
| 10 mM | 0.30 mL | 1.52 mL | 3.05 mL |
| 50 mM | 0.06 mL | 0.30 mL | 0.61 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Seeman and Van Tol DA receptor pharmacology. TiPS 1994 PMID: 7940991
- Levesque Aminotetralin drugs and D3 receptor fuctions. Biochem.Pharmacol. 1996 PMID: 8759022
- Levesque Identification, characterization, and localization of the DA D3 receptor in rat brain using [3H]-7-hydroxy-N,N-di-n-propyl-2-aminotetralin. Proc.Natl.Acad.Sci.U.S.A. 1992 PMID: 1518841
- Daly and Waddington Behavioural effects of the D3 DA receptor agonist 7-OH-DPAT in relation to other D2-like agonists. Neuropharmacology 1993 PMID: 8321432
Product Specific Notices for 7-Hydroxy-DPAT hydrobromide
For research use only
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