Activin B/Inhibin beta B 293T Cell Transient Overexpression Lysate
Novus Biologicals, part of Bio-Techne | Catalog # H00003625-T02
Key Product Details
Species
Human
Applications
Western Blot
Product Summary for Activin B/Inhibin beta B 293T Cell Transient Overexpression Lysate
Quality control test: Transient overexpression cell lysate was tested with Anti-INHBB antibody by Western Blots. Plasmid: pCMV-INHBB full-length
Product Specifications
Specificity
Activin B/Inhibin beta B 293T Cell Transient Overexpression Lysate(Denatured)
Type
293T Cell Transient Overexpression
Protein State
Denatured
Formulation, Preparation, and Storage
Formulation
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Concentration
mg/ml
Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at -80C. Avoid freeze-thaw cycles.
Background: Activin B
Activin B is a TGF-beta superfamily cytokine that regulates cellular migration by inducing actin stress fiber formation. It signals through heterodimeric receptor complexes composed of type I (Activin RIA or RIB) and type II (Activin RIIA or RIIB) transmembrane Ser/Thr kinases. It also modulates signaling through E-Cadherin and Integrin beta 3. Activin B upregulation is associated with tumor cell adhesion, migration, and metastasis. It also promotes wound healing through increased cellular migration. Activin B additionally induces hair follicle formation and expression of Hepicin in the liver, but it inhibits lipolysis in adipocytes and glucose-stimulated calcium influx in pancreatic beta cells. Alterations of Activin B serum levels of Activin B are associated with ectopic pregnancy and chronic fatigue syndrome, and it is upregulated in alveolar epithelial cells in pulmonary fibrosis.
Long Name
Inhibin Subunit Beta B
Alternate Names
activin AB beta polypeptide, Activin Beta B, Activin beta-B chain, INHBB, Inhibin Beta B, inhibin beta B chain, Inhibin Subunit Beta B, inhibin, beta B, inhibin, beta B (activin AB beta polypeptide), Inhibin, beta-2
Gene Symbol
INHBB
Additional Activin B Products
Product Documents for Activin B/Inhibin beta B 293T Cell Transient Overexpression Lysate
Product Specific Notices for Activin B/Inhibin beta B 293T Cell Transient Overexpression Lysate
This product is produced by and distributed for Abnova, a company based in Taiwan.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.
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