tri-GalNAc-C5-AF647
Tocris Bioscience, part of Bio-Techne | Catalog # 7901
Fluorescent ASGPR ligand. Application: flow cytometry, fluorescence microscopy
Key Product Details
Description
Fluorescent ASGPR ligand. Application: flow cytometry, fluorescence microscopy
Product Description
Key information: tri-GalNAc-C5-AF647 is a fluorescent asialoglycoprotein receptor (ASGPR) ligand. Suitable for live-cell imaging.Used for: lysosomal uptake in live-cell imaging, isolating hepatocytes due to its uptake via ASGPR receptor.
Application: flow cytometry, fluorescence microscopy.
Properties and Photophysical Data: suitable for multiplexing and can be combined with DAPI (Cat. No. 5748) counter-staining. Excitation and emission maxima (λ) are 663 and 684 nm, respectively.
Optical Data
| λabs | 663 nm |
| λem | 684 nm |
| Cell Permeable | Yes |
| Application | Flow Cytometry, Fluorescence Microscopy |
Spectra Viewer
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Product Specifications
Molecular Weight
2456.74
Formula
C103H162N16O44S4
Storage
Store at -20°C
Purity
≥90%
InChI Key
YADZNIHLQXJZAN-PPECRGGSSA-N
SMILES
O=C(NC(COCC1=CN(N=N1)CCOCCOCCOCCO[C@H]2O[C@H]([C@@H](O)[C@@H](O)[C@@H]2NC(C)=O)CO)(COCC3=CN(N=N3)CCOCCOCCOCCO[C@@H]4O[C@@H]([C@H](O)[C@H](O)[C@H]4NC(C)=O)CO)COCC5=CN(N=N5)CCOCCOCCOCCO[C@H]6O[C@H]([C@@H](O)[C@@H](O)[C@@H]6NC(C)=O)CO)CCCCCNC(CCCCCC7(C(/C=C/C=C/C=C8C(C)(C9=C(N\8CCCS(=O)(O)=O)C=CC(S(=O)(O)=O)=C9)C)=[N+](C%10=C7C=C(C=C%10)S(=O)(O)=O)CCCS(=O)([O-])=O)C)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 24.57 | 10 |
Preparing Stock Solutions
for tri-GalNAc-C5-AF647
The following data is based on the product molecular weight 2456.74
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 4.07 mL | 20.35 mL | 40.70 mL |
| 0.5 mM | 0.81 mL | 4.07 mL | 8.14 mL |
| 1 mM | 0.41 mL | 2.04 mL | 4.07 mL |
| 5 mM | 0.08 mL | 0.41 mL | 0.81 mL |
Calculators
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Background References
References are publications that support the biological activity of the product.
- Sanhueza Efficient liver targeting by polyvalent display of a compact ligand for the asialoglycoprotein receptor. J.Am.Chem.Soc. 2017 PMID: 28230359
Product Specific Notices for tri-GalNAc-C5-AF647
For research use only
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