FFN 511
Tocris Bioscience, part of Bio-Techne | Catalog # 3878
Fluorescent substrate for VMAT2
Discontinued Product
3878 has been discontinued.
View all Fluorescent Transporter Probes products.
Key Product Details
Description
Fluorescent substrate for VMAT2
Product Description
FFN 511 is a fluorescent false neurotransmitter (FFN). Targets neuronal vesicular monoamine transporter (VMAT) 2; inhibits serotonin binding to VMAT2 (IC50 = 1 μM). Excitation and emission maxima are 406 and 501 nm in pH 7 buffer, respectively.Licensing Information
Sold with the permission of Columbia UniversitySpectra Viewer
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Product Specifications
Molecular Weight
284.35
Formula
C17H20N2O2
Storage
Store at +4°C
Purity
≥99% (HPLC)
Chemical Name
9-(2-Aminoethyl)-2,3,6,7-tetrahydro-1H,5H,11H-[1]-benzopyrano[6,7,8-ij]quinolizin-11-one
CAS Number
1004548-96-2
PubChem ID
23725121
InChI Key
SKTIZSRPCXRDHX-UHFFFAOYSA-N
SMILES
NCCC(C1=C(O4)C3=C2C(CCCN2CCC3)=C1)=CC4=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| 1eq. HCl | 7.11 | 25 | |
| DMSO | 1.42 | 5 |
Preparing Stock Solutions
for FFN 511
The following data is based on the product molecular weight 284.35
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.25 mM | 14.07 mL | 70.34 mL | 140.67 mL |
| 1.25 mM | 2.81 mL | 14.07 mL | 28.13 mL |
| 2.5 mM | 1.41 mL | 7.03 mL | 14.07 mL |
| 12.5 mM | 0.28 mL | 1.41 mL | 2.81 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Zhang DA release at individual presynaptic terminals visualized with FFNs. J.Vis.Exp. 2009 PMID: 19721412
- Gubernator Fluorescent false neurotransmitters visualize DA release from individual presynaptic terminals. Science 2009 PMID: 19423778
Product Specific Notices for FFN 511
For research use only
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