Mouse Semaphorin 3D (NP_083158) VersaClone cDNA

R&D Systems, part of Bio-Techne | Catalog # RDC2569

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Key Product Details

Species

Mouse

Accession Number

NP_083158

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Semaphorin 3D

The Semaphorins make up the largest family of axon guidance cues yet described. Semaphorins are divided into 8 classes (classes 3-7 found in vertebrates). Class 3 Semaphorins are secreted, classes 4 through 6 are transmembrane proteins, and class 7 are membrane associated via glycosylphosphatidylinositol (GPI) linkage. They are characterized structurally by a conserved ~400 amino acid sema domain. They are classically described as collapsing factors and mediators of axon repulsion, although they may also act as context-dependent chemoattractants. Semaphorins have been shown to have roles in cardiovascular development and in the regulation of immune cell antigen presentation. Receptors or receptor complexes that mediate semaphorin signaling include proteins of the Neuropilin and Plexin families.

Alternate Names

coll-2, Collapsin 2, Sema-Z2, SEMA3D, Semaphorin-3D

Entrez Gene IDs

223117 (Human); 108151 (Mouse); 246262 (Rat)

Gene Symbol

SEMA3D

UniProt

NP_083158

Additional Semaphorin 3D Products

Product Documents for Mouse Semaphorin 3D (NP_083158) VersaClone cDNA

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Product Specific Notices for Mouse Semaphorin 3D (NP_083158) VersaClone cDNA

For research use only

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