human MBTPS1/SKI-1 (NP_003782.1) VersaClone cDNA

R&D Systems, part of Bio-Techne | Catalog # RDC3632

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Key Product Details

Species

Human

Accession Number

NP_003782.1

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: MBTPS1/SKI-1

The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq]

Long Name

Membrane Bound Transcription Factor Peptidase, Site 1

Alternate Names

KIAA0091, PCSK8, S1P, SEDKF, SKI-1

Entrez Gene IDs

8720 (Human)

Gene Symbol

MBTPS1

UniProt

NP_003782.1

Additional MBTPS1/SKI-1 Products

Product Documents for human MBTPS1/SKI-1 (NP_003782.1) VersaClone cDNA

Product Datasheets

Certificate of Analysis

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Product Specific Notices for human MBTPS1/SKI-1 (NP_003782.1) VersaClone cDNA

For research use only

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