PRELP is encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq]

Long Name

Proline-arginine-Rich End Leucine-rich repeat Protein

Alternate Names

MST161, MSTP161, Prolargin, SLRR2A

Gene Symbol

PRELP

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Product Specific Notices for PRELP Antibody (754636) [Janelia Fluor® 646]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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PRELP Antibody (754636) [Janelia Fluor® 646]

Novus Biologicals, part of Bio-Techne | Catalog # FAB64471J

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Applications for PRELP Antibody (754636) [Janelia Fluor® 646]

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Background: PRELP