p63/TP73L Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84895

Novus Biologicals, part of Bio-Techne
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NBP1-84895-25ul
NBP1-84895
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Predicted:

Mouse (99%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all p63/TP73L Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids:CACPGRDRKADEDSIRKQQVSDSTKNGDAFRQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQ

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for p63/TP73L Antibody

p63/TP73L Antibody Immunohistochemistry-Paraffin: p63/TP73L Antibody [NBP1-84895]

Immunohistochemistry-Paraffin: p63/TP73L Antibody [NBP1-84895]

Analysis in human skin and kidney. Corresponding TP63 RNA-seq data are presented for the same tissues.
p63/TP73L Antibody Immunohistochemistry-Paraffin: p63/TP73L Antibody [NBP1-84895]

Immunohistochemistry-Paraffin: p63/TP73L Antibody [NBP1-84895]

Staining of human placenta shows strong nuclear positivity in cytotrophoblasts.
p63/TP73L Antibody Immunohistochemistry-Paraffin: p63/TP73L Antibody [NBP1-84895]

Immunohistochemistry-Paraffin: p63/TP73L Antibody [NBP1-84895]

Staining of human kidney shows no nuclear positivity in cells in tubules as expected.
View 3 more images

Applications for p63/TP73L Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: PFA/Triton X-100

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: p63/TP73L

The p63 gene, a homologue of the tumor suppressor p53, is highly expressed in the basal or progenitor layers of many epithelial tissues. P63 shows remarkable structural similarity to p53 and to the related p73 gene. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis.

Long Name

Tumor Protein 63

Alternate Names

EEC3, KET, OFC8, p40, p51, p73L, SHFM4, TP63, TP73L

Gene Symbol

TP63

Additional p63/TP73L Products

Product Documents for p63/TP73L Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for p63/TP73L Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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