Mouse Afamin Alexa Fluor® 594-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # AF8119T
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot
Label
Alexa Fluor 594 (Excitation = 590 nm, Emission = 617 nm)
Antibody Source
Polyclonal Sheep IgG
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Afamin
Leu22-Met608
Accession # O89020
Leu22-Met608
Accession # O89020
Specificity
Detects mouse Afamin in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human Afamin is observed.
Clonality
Polyclonal
Host
Sheep
Isotype
IgG
Applications for Mouse Afamin Alexa Fluor® 594-conjugated Antibody
Application
Recommended Usage
Western Blot
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
Background: Afamin
Afamin, also known as AFM or alpha-Albumin, is an 84-88 kDa secreted monomeric glycoprotein member of the Alb/albumin family of molecules. Expressed by hepatocytes, CNS endothelial cells and osteoclasts, Afamin circulates in the blood at low μg/mL concentrations. Afamin is known to bind and transport vitamin E, particularly under conditions where lipoprotein is limited. This is likely to be important in follicular fluid and CSF. Afamin also serves as an osteoclast-derived chemoattractant for preosteoblasts, providing a rationale for the observation that bone formation often follows bone resorption. Mature mouse Afamin is 587 amino acids (aa) in length (aa 22-608). It contains three consecutive albumin domains (aa 22-210, 211-403 and 404-599) that contain characteristic 5 or 6 intrachain disulfide bonds. Full-length mouse Afamin shares 67% aa sequence identity with human Afamin.
Alternate Names
AFM, ALB2, ALBA, ALF
Gene Symbol
AFM
UniProt
Additional Afamin Products
Product Specific Notices for Mouse Afamin Alexa Fluor® 594-conjugated Antibody
This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.
For research use only
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