Human Phospho-MSK1 (S212) Alexa Fluor® 750-conjugated Antibody

Name: Human Phospho-MSK1 (S212) Alexa Fluor® 750-conjugated Antibody
Brand: R&D Systems
SKU: AF1036S

R&D Systems, part of Bio-Techne | Catalog # AF1036S

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Product Datasheet / COA

Key Product Details

Species Reactivity:

Human

Immunogen:

Phosphopeptide containing human MSK1 S212 site

Applications:

Immunohistochemistry, Western Blot

Label:

Alexa Fluor 750 (Excitation=749 nm, Emission=775 nm)

Specificity:

Detects human MSK1 when phosphorylated at S212.

View Full Technical Details for Human Phospho-MSK1 (S212) Alexa Fluor® 750-conjugated Antibody

Technical Data
Citations / Reviews

Applications

	Recommended Concentration	Sample
Western Blot	Optimal dilution of this antibody should be experimentally determined.
Immunohistochemistry	Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application.

Formulation, Preparation and Storage

Purification	Antigen Affinity-purified
Formulation	Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

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Background: MSK1

Mitogen- and stress-activated protein kinase 1 (MSK1), also known as ribosomal protein S6 kinase 5 (RPS6KA5), belongs to the AGC family of kinases. Both MSK1 and the related MSK2, also known as RSKB and RPS6KA4, have two kinase domains connected by a regulatory linker region, and are activated by the mitogen-activated protein kinases ERK1, ERK2, and p38. Nuclear MSK phosphorylates and activates a number of transcription factors, including ATF1 and CREB.

Item	Value
Long Name	Mitogen- and Stress-activated Protein Kinase 1
Entrez Gene IDs	9252 (Human); 73086 (Mouse)
Alternate Names	EC 2.7.11, MGC1911,90 kDa ribosomal protein S6 kinase 5, MSK1, MSK1EC 2.7.11.1, MSPK1, Nuclear mitogen- and stress-activated protein kinase 1, RLPK, RPS6KA5, RSK-like protein kinase, RSKL, S6K-alpha-5, ribosomal protein S6 kinase alpha-5, ribosomal protein S6 kinase, 90kD, polypeptide 5, ribosomal protein S6 kinase, 90kDa, polypeptide 5

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