Human Pentraxin 3/TSG-14 Antibody
R&D Systems, part of Bio-Techne | Catalog # PP-PPJ0069-00
Key Product Details
Species Reactivity
Human
Applications
ELISA, Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2A Clone # PPJ0069
Product Specifications
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Applications for Human Pentraxin 3/TSG-14 Antibody
Application
Recommended Usage
ELISA
Western Blot
Formulation, Preparation, and Storage
Formulation
A liquid formulation in physiologic saline with 0.1% NaN3.
Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Pentraxin 3/TSG-14
Pentraxin 3 (PTX3), also known as TNF-stimulated gene 14 (TSG-14), is a secreted glycoprotein belonging to the Pentraxin family of proteins. It is the prototypical long Pentraxin, exhibiting a C-terminal Pentraxin domain characteristic of the family, and a unique N-terminal domain. It is produced by several cell types including endothelial and mononuclear cells. PTX3 acts as a pattern recognition receptor with non-redundant roles in the innate immune response to several microbial agents including the fungal pathogen Aspergillus fumigatus. Overexpression leads to enhanced pro-inflammatory responses. PTX3 is induced in response to LPS and inflammatory cytokines including TNF-alpha and IL-1 beta.
Long Name
Tumor Necrosis Factor Stimulated Gene 14
Alternate Names
PTX3, TSG-14, TSG14
Gene Symbol
PTX3
Additional Pentraxin 3/TSG-14 Products
Product Documents for Human Pentraxin 3/TSG-14 Antibody
Product Specific Notices for Human Pentraxin 3/TSG-14 Antibody
For research use only
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