Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for the elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A5 is an integral plasma membrane protein which functions as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. Mutations in SLC22A5 are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy.

Long Name

Solute Carrier Family 22 (Organic Cation/Carnitin Transporter) Member 5

Alternate Names

CDSP, OCTN2VT, SCD, SLC22A5

Entrez Gene IDs

6584 (Human); 20520 (Mouse); 29726 (Rat)

Gene Symbol

SLC22A5

UniProt

O76082 (Human)

Additional OCTN2/SLC22A5 Products

Product Documents

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

Citations
Reviews

Spectra Viewer
Flow Cytometry

Human OCTN2/SLC22A5 Alexa Fluor™ Plus 647-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB11004AFP647

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

View all OCTN2/SLC22A5 Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Applications

Flow Cytometry

Formulation, Preparation, and Storage

Formulation

Shipping

Stability & Storage

Background: OCTN2/SLC22A5