Human/Mouse Serpin I1 Alexa Fluor™ Plus 405-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB3124AFP405
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human, Mouse
Applications
Western Blot
Label
Alexa Fluor Plus 405 (Excitation = 404 nm, Emission = 455 nm)
Antibody Source
Monoclonal Rat IgG2A Clone # 437016
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Serpin I1
Specificity
Detects human and mouse SerpinI1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross reactivity with recombinant mouse Serpin I1 is observed and no cross-reactivity with recombinant human Serpin A1, A3, A4, A5, A12, B6, B8, B9, C1, D1, F2, G1, or I2 is observed.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications
Application
Recommended Usage
Western Blot
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
Background: Serpin I1
Serpin I1, also known as neuroserpin, is a secreted serine protease inhibitor predominantly expressed in the brain. Serpin I1 defects cause familial encephalopathy with neuroserpin inclusion bodies (FEN1B), an autosomal dominant dementia. The amino acid sequence of human Serpin I1 is 99%, 93%, 88%, 86% and 80% identical to that of chimpanzee, dog, rat, mouse and chicken.
Alternate Names
Neuroserpin, PI12
Gene Symbol
SERPINI1
UniProt
Additional Serpin I1 Products
Product Specific Notices
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
For research use only
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