Human LXR alpha/NR1H3 Antibody (Clone K8607)

Detection of LXR alpha/NR1H3 by Western Blot

YTHDF2 downregulates LXRA and HIVEP2 through m6A-dependent mRNA decay.a Western blotting of LXR alpha and HIVEP2 in GSC11 cells stably transfected with control shRNA or two YTHDF2 shRNAs. b Western blotting of LXR alpha and HIVEP2 in LN229/EGFRvIII tet-on cells cul Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/33420027), licensed under a CC-BY license. Not internally tested by R&D Systems.

Detection of LXR alpha/NR1H3 by Western Blot

LXR alpha and HIVEP2 are functionally essential targets of YTHDF2 in cell proliferation, invasion, cholesterol dysregulation, and tumorigenesis of GBM cells. A Western blotting of YTHDF2, LXR alpha, and HIVEP2 in GSC11 cells stably expressing shCtrl, shYTHDF2, or shYTHDF2 plus shLXRA or/and shHIVEP2. Representative blot of three independent experiments is shown. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/33420027), licensed under a CC-BY license. Not internally tested by R&D Systems.

Detection of LXR alpha/NR1H3 by Western Blot

YTHDF2 downregulates LXRA and HIVEP2 through m6A-dependent mRNA decay. b Western blotting of LXR alpha and HIVEP2 in LN229/EGFRvIII tet-on cells cultured with vehicle or Doxycycline and transfected with control siRNA or two individual YTHDF2 siRNAs Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/33420027), licensed under a CC-BY license. Not internally tested by R&D Systems.