Detects human DSPG3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse DSPG3 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for Human DSPG3 Alexa Fluor™ Plus 555-conjugated Antibody

Application

Recommended Usage

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: DSPG3

Human DSPG3 (also PG-Lb and epiphycan) is a 95‑100 kDa class III subfamily member of the SLRP family of molecules. It is synthesized as a 322 aa precursor that contains a 19 aa signal sequence and a 303 aa mature region. The mature molecule contains two intrachain disulfide bonds that flank six leucine-rich repeats lying between aa 135-301. There is a potential for both O- and N-linked glycosylation. DSPG3 is found principally in cartilage. Mature human DSPG3 is 85%, 96%, 95% and 84% aa identical to rat, dog, cow and mouse DSPG3, respectively.

Long Name

Dermatan Sulfate Proteoglycan 3

Alternate Names

Epiphycan, EPYC, PG-Lb, SLRR3B

Entrez Gene IDs

1833 (Human); 13516 (Mouse)

Gene Symbol

EPYC

UniProt

Q99645

Additional DSPG3 Products

Product Documents

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Human DSPG3 Alexa Fluor™ Plus 555-conjugated Antibody

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

Citations
Reviews

Human DSPG3 Alexa Fluor™ Plus 555-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB3110AFP555

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

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Product Specifications

Immunogen

Specificity