Human CCK Alexa Fluor™ Plus 647-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB11040AFP647
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry, Immunocytochemistry
Label
Alexa Fluor Plus 647 (Excitation = 658 nm, Emission = 675 nm)
Antibody Source
Recombinant Monoclonal Rabbit IgG Clone # 2753A
Product Specifications
Specificity
Detects human CCK in direct ELISAs.
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Applications for Human CCK Alexa Fluor™ Plus 647-conjugated Antibody
Application
Recommended Usage
Immunocytochemistry
Optimal dilution of this antibody should be experimentally determined.
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
Background: CCK
Cholecystokinin (CCK) is a peptide hormone secreted by the gastrointestinal system that stimulates the digestion of protein and fat. CCK is synthesized and secreted by enteroendocrine cells of the duodenum and acts as a hunger suppressant. CCK participates in several processes such as digestion, satiety, and anxiety. CCK is also found extensively throughout the central nervous system with anxiogenic, panicogenic and hallucinogenic effects. Receptors of CCK are found in the central nervous system specifically in the hippocampus, cerebral cortex, and striatum.
References
Lenka A., Arumugham SS., Christopher R., Pal PK, "Genetic Substrates of Psychosis in Patients with Parkinson's Disease: A Critical Review". Journal of the Neurological Sciences. 2016 May; 364: 33-41. Zwanzger P., Domschke K., Bradwejn J., "Neuronal Network of Panic Disorder: The Role of the Neuropeptide Cholecystokinin". Depression and Anxiety. 2012 Sep. 29(9): 762-74. Okonkwo O., Zezoff D., Adeyinka A., "Biochemistry, Cholecystokinin". StatPearls. 2021 Jan. Available from: https://www.ncbi.nlm.nih.gov/books/NBK534204/.
Long Name
Cholecystokinin
Alternate Names
cholecystokinin, MGC117187
Entrez Gene IDs
885 (Human)
Gene Symbol
CCK
UniProt
Additional CCK Products
Product Specific Notices for Human CCK Alexa Fluor™ Plus 647-conjugated Antibody
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
For research use only
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