Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Monoclonal Rabbit IgG Clone # 2880B

View all 5-HT2B Antibodies »

Product Specifications

Immunogen

Synthetic peptide containing human 5- HTR2B
Accession # P41595

Specificity

Detects human 5-HTR2B in direct ELISA.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Human 5-HT2B APC-conjugated Antibody

Detection of 5-HT2B in HEK293 cell transfected with 5-HT2B and eGFP vs irrelevant cells by Flow Cytometry.

HEK293 cell transfected with 5-HT2B and eGFP vs irrelevant was stained with eGFP and Rabbit Anti-Human 5-HT2B APC-conjugated Monoclonal Antibody (Catalog # FAB11297A) in 5-HT2B transfectants (A) or (B) irrelevant transfectants. View our protocol for Staining Membrane-associated Proteins.

Applications for Human 5-HT2B APC-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: HEK293 cell transfected with 5-HT2B and eGFP vs irrelevant

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

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Formulation, Preparation, and Storage

Purification

Protein A or G purified from ascites

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: 5-HT2B

HTR2B is a G-protein coupled receptor for serotonin. The 5HT2 receptors mediate many of the central and peripheral physiologic functions of serotonin. 5HT2B plays a role in the regulation of dopamine and serotonin release, serotonin uptake and in the regulation of extracellular dopamine and serotonin levels. It also plays a role in pulmonary vasoconstriction and regulating cardiac structure and functions. 5HT2B receptors were shown to be expressed in human failing heart and have been strongly implicated in drug induced valvular heart disease.

Long Name

5-Hydroxytryptamine Receptor 2B

Alternate Names

5HT2B, HTR2B

Entrez Gene IDs

3357 (Human); 15559 (Mouse); 29581 (Rat)

Gene Symbol

HTR2B

UniProt

P41595

Additional 5-HT2B Products

Product Documents for Human 5-HT2B APC-conjugated Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human 5-HT2B APC-conjugated Antibody

For research use only

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