FGL2/Fibroleukin Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87198

Novus Biologicals, part of Bio-Techne
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NBP1-87198
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FGL2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RNGLLLPSTGAPGEVGDNRVRELESEVNKLSSELKNAKEEINVLHGRLEKLNLVNMNNIENYVDSKVANLTFVVNSLDGKCSKCP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit FGL2/Fibroleukin Antibody - BSA Free (NBP1-87198) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for FGL2/Fibroleukin Antibody - BSA Free

Immunohistochemistry-Paraffin: FGL2/Fibroleukin Antibody [NBP1-87198]

Immunohistochemistry-Paraffin: FGL2/Fibroleukin Antibody [NBP1-87198]

Immunohistochemistry-Paraffin: FGL2/Fibroleukin Antibody [NBP1-87198] - Staining of human spleen shows strong cytoplasmic positivity in cells in red pulp.
Immunohistochemistry-Paraffin: FGL2/Fibroleukin Antibody [NBP1-87198]

Immunohistochemistry-Paraffin: FGL2/Fibroleukin Antibody [NBP1-87198]

Immunohistochemistry-Paraffin: FGL2/Fibroleukin Antibody [NBP1-87198] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry-Paraffin: FGL2/Fibroleukin Antibody [NBP1-87198]

Immunohistochemistry-Paraffin: FGL2/Fibroleukin Antibody [NBP1-87198]

Immunohistochemistry-Paraffin: FGL2/Fibroleukin Antibody [NBP1-87198] - Analysis in human spleen and pancreas tissues. Corresponding FGL2/Fibroleukin RNA-seq data are presented for the same tissues.
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Applications for FGL2/Fibroleukin Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20-1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FGL2

FGL2 (fibrinogen-like protein 2), also called fibroleukin, is a 64-70 kDa secreted glycoprotein of the Fibrinogen-like superfamily. In the presence of acidic phospholipids and calcium, FGL2 has prothrombinase activity and acts as a procoagulant. In soluble form, FGL2 promotes T regulatory (Treg) activity and suppresses DC, T, and B cell immune reactivity, acting as an immune suppressor. A 260-280 aa FGL2 complex is thought to be a homotetramer.

Long Name

Fibrinogen-like 2

Alternate Names

Fibroleukin, T49

Gene Symbol

FGL2

Additional FGL2 Products

Product Documents for FGL2/Fibroleukin Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FGL2/Fibroleukin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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