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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Neutralization, Immunocytochemistry, In ovo assay

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # 47109

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

E. coli-derived recombinant mouse FGF-8b
Gln23-Arg215
Accession # NP_001159834

Specificity

Detects human and mouse FGF-8 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human  (rh) FGF-5, rhFGF-7, and rhFGF-9 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for FGF-8 Antibody (47109) [FITC]

Application
Recommended Usage

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

In ovo assay

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Neutralization

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from ascites

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: FGF-8

Fibroblast Growth Factor 8 (FGF-8) is widely expressed during embryogenesis where it plays an organizing and inducing role during gastrulation and regulates patterning of the midbrain/hindbrain, eye, ear, limbs, and heart. Multiple alternative splice isoforms play distinct roles in development as well as epithelial-mesenchymal transition. They also show differential agonist activity towards the various isoforms of FGF R1, R2, R3, R4, and R5. FGF-8 is weakly expressed in yhe adult reproductive and genitourinary tract, peripheral leukocytes, and bone marrow hematopoietic cells.

Long Name

Fibroblast Growth Factor 8

Alternate Names

AIGF, FGF8, HBGF-8

Gene Symbol

FGF8

Additional FGF-8 Products

Product Documents for FGF-8 Antibody (47109) [FITC]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FGF-8 Antibody (47109) [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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