Endomucin/Mucin -14 Antibody (DMC473) - Chimeric
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-48356
Recombinant Monoclonal Antibody
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Human IgG1 Clone # DMC473
Concentration
LYOPH mg/ml
Product Specifications
Immunogen
Endomucin/Mucin -14 recombinant protein expressed in mammalian cells (Accession# Q9ULC0). The exact amino acid sequence is proprietary.
Clonality
Monoclonal
Host
Human
Isotype
IgG1
Description
This product is shipped at ambient temperature. Store at -20C to -80C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80C (Avoid repeated freezing and thawing).
Applications for Endomucin/Mucin -14 Antibody (DMC473) - Chimeric
Application
Recommended Usage
Flow Cytometry
1:100
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified from cell culture supernatant
Reconstitution
.
Formulation
PBS, pH 7.4, 5-8% Trehalose
Preservative
Trehalose
Concentration
LYOPH mg/ml
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C in powder form. Store at -80C once reconstituted.
Background: Endomucin
Endomucin (endothelial sialomucin; also Endomucin-1/2 and Mucin-14) is an 80 - 120 kDa glycoprotein member of the Endomucin family of proteins. It is expressed on endothelial cells and depending upon its glycosylation pattern, can serve as either a pro- or anti-adhesive molecule.
Mouse Endomucin precursor is 261 amino acids in length. It is type I transmembrane protein that contains a 170 aa extracellular domain (ECD) (aa 21 - 190) and a 50 aa cytoplasmic region. Three splice variants exist in the ECD of Endomucin. One shows a deletion of aa 91 - 141, a second shows a one aa substitution for aa 91 - 129, and a third shows a one aa substitution for aa 129 - 142. Over aa 21 - 90, mouse Endomucin shares 60% and 30% aa identity with rat and human Endomucin, respectively.
Alternate Names
EMCN, EMCN2, MUC-14
Gene Symbol
EMCN
Additional Endomucin Products
Product Documents for Endomucin/Mucin -14 Antibody (DMC473) - Chimeric
Product Specific Notices for Endomucin/Mucin -14 Antibody (DMC473) - Chimeric
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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