Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA Standard (Matched Pair), ELISA Capture (Matched Antibody Pair), ELISA Detection (Matched Antibody Pair)

Label

DyLight 680 (Excitation = 692 nm, Emission = 712 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # 173103

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all EDA2R/TNFRSF27/XEDAR Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human EDA2R/TNFRSF27/XEDAR
Met1-Glu136
Accession # Q9HAV5

Specificity

Detects human EDA2R/TNFRSF27/XEDAR in ELISAs and Western blots. In direct ELISAs, no cross‑reactivity with recombinant human (rh) 41BB, rhBAFF R, rhCD27, rhCD30, rhCD40, rhDR‑3, rhDR‑6, rhEDAR, rhFAS, rhGITR, rhHVEM, rhLTR‑b, rhNGFR, rhOPG, rhOX40 R, rhRANK, rhRELT, rhTAJ, rhTNF R1, rhTNF RII, rhTRADD, rhTRAIL R1, rhTRAIL R2, rhTRAIL R3, rhTRAIL R4, rhTWEAK R, recombinant mouse (rm) DcTRAIL R1, and rmDcTrail R2 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for EDA2R/TNFRSF27/XEDAR Antibody (173103) [DyLight 680]

Application
Recommended Usage

ELISA Capture (Matched Antibody Pair)

Optimal dilutions of this antibody should be experimentally determined.

ELISA Detection (Matched Antibody Pair)

Optimal dilutions of this antibody should be experimentally determined.

ELISA Standard (Matched Pair)

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: EDA2R/TNFRSF27/XEDAR

EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support.

Long Name

Ectodysplasin A2 Receptor

Alternate Names

EDAA2R, TNFRSF27, XEDAR

Gene Symbol

EDA2R

Additional EDA2R/TNFRSF27/XEDAR Products

Product Documents for EDA2R/TNFRSF27/XEDAR Antibody (173103) [DyLight 680]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for EDA2R/TNFRSF27/XEDAR Antibody (173103) [DyLight 680]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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