DHCR7 Antibody (HL2764)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-48728

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-48728
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # HL2764

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DHCR7 Antibodies »

Product Specifications

Immunogen

Recombinant fragment of human DHCR7.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit DHCR7 Antibody (HL2764) (NBP3-48728) is a recombinant monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for DHCR7 Antibody (HL2764)

DHCR7 Antibody (HL2764)

Western Blot: DHCR7 Antibody (HL2764) [NBP3-48728] -

MCF-7 cytosol and membrane extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with DHCR7 antibody [HL2764] (NBP3-48728) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody
DHCR7 Antibody (HL2764)

Western Blot: DHCR7 Antibody (HL2764) [NBP3-48728] -

Non-transfected (-) and transfected (+) Boiled and unboiled 293T whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with DHCR7 antibody [HL2764] (NBP3-48728) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Applications for DHCR7 Antibody (HL2764)

Application
Recommended Usage

Western Blot

1:500-1:10000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DHCR7

The DHCR7 gene encodes delta-7-sterol reductase (EC 1.3.1.21), the penultimate enzyme of mammalian sterol biosynthesis that converts 7-dehydrocholesterol (7-DHC) to cholesterol. This enzyme removes the C(7-8) double bond introduced by the sterol delta8-delta7 isomerases. In addition, its role in drug-induced malformations is known: inhibitors of the last step of cholesterol biosynthesis such as AY9944 and BM15766 severely impair brain development (Moebius et al., 1998 [PubMed 9465114]).[supplied by OMIM]

Alternate Names

7-dehydrocholesterol reductase, 7-DHC reductase, D7SR, delta-7-dehydrocholesterol reductase, EC 1.3.1, EC 1.3.1.21, Putative sterol reductase SR-2, SLOS, Smith-Lemli-Opitz syndrome, Sterol Delta(7)-reductase, sterol delta-7-reductase

Gene Symbol

DHCR7

Additional DHCR7 Products

Product Documents for DHCR7 Antibody (HL2764)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for DHCR7 Antibody (HL2764)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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