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GRIN2B/NMDAR2B Products

NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity. NMDARs are heteromeric complexes of multiple subunits: NR1, which occurs as eight distinct isoforms as the result of alternate splicing; NR2 (NR2A, B, C and D are encoded by four related genes, several of which also display multiple splice forms); and NR3 (NR3A and B also have several splice forms). The particular combination of subunits determines the functional characteristics of the receptor.

23 results for "GRIN2B/NMDAR2B" in Products

GRIN2B/NMDAR2B Products

NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity. NMDARs are heteromeric complexes of multiple subunits: NR1, which occurs as eight distinct isoforms as the result of alternate splicing; NR2 (NR2A, B, C and D are encoded by four related genes, several of which also display multiple splice forms); and NR3 (NR3A and B also have several splice forms). The particular combination of subunits determines the functional characteristics of the receptor.

23 results for "GRIN2B/NMDAR2B" in Products

WB, IHC, IP
WB
WB
Catalog #: RDC1221

Non-competitive NMDA antagonist; acts at ion channel site

Broad spectrum glutamatergic antagonist

NMDA antagonist; antidepressant; may not display psychotomimetic or addictive side effects of (S)-ketamine

Non-competitive NMDA antagonist; also σ ligand

GluN2B-selective NMDA antagonist

Glucosidase α inhibitor (intestinal)

GluN2B-selective NMDA antagonist

NMDA antagonist; acts at ion channel site

Highly potent NMDA antagonist

Potent and selective NMDA antagonist; acts at the glycine site

Positive allosteric modulator of NMDA receptors; acts in transmembrane domain

Potent and noncompetitive NMDA antagonist

Competitive NMDA antagonist

Potent NMDA antagonist; acts at glycine site

NMDA antagonist; acts at glycine site

Specific σ ligand, NMDA antagonist

Potent and selective NMDA antagonist

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