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CCR8 Products

CCR8 is a G protein-coupled receptor member of the CC chemokine subfamily of receptors. Human CCR8 is 355 amino acids (aa) in length with a predicted molecular weight of 41 kDa. Mouse and rat CCR8 share 71% aa sequence identity with the human protein. Most chemokine receptors exhibit promiscuous binding properties whereby several different chemokines signal through the same receptor. Chemokine ligand receptor binding results in G protein activation as well as the activation of downstream signaling cascades, including the Akt and NFkB pathways. Chemokine receptors mediate the chemotactic actions of chemokine ligands and activation of these receptors leads to cytoskeleton rearrangement and chemotactic cell migration.

68 results for "CCR8" in Products

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CCR8 Products

CCR8 is a G protein-coupled receptor member of the CC chemokine subfamily of receptors. Human CCR8 is 355 amino acids (aa) in length with a predicted molecular weight of 41 kDa. Mouse and rat CCR8 share 71% aa sequence identity with the human protein. Most chemokine receptors exhibit promiscuous binding properties whereby several different chemokines signal through the same receptor. Chemokine ligand receptor binding results in G protein activation as well as the activation of downstream signaling cascades, including the Akt and NFkB pathways. Chemokine receptors mediate the chemotactic actions of chemokine ligands and activation of these receptors leads to cytoskeleton rearrangement and chemotactic cell migration.

68 results for "CCR8" in Products

Clone 191704 was used by HLDA to establish CD designation

Clone 191704 was used by HLDA to establish CD designation

Flow, CyTOF-ready, Neut

Clone 191704 was used by HLDA to establish CD designation

Catalog #: FAB8324R
Flow

Recombinant Monoclonal Antibody.

Recombinant Monoclonal Antibody.

Flow

Clone 191704 was used by HLDA to establish CD designation

WB
Catalog #: FAB1429G
Flow

Recombinant Monoclonal Antibody.

IHC, WB
Catalog #: FAB8324N
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB8324U
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB8324T
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB8324G
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB8324V
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB8324S
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB1429R
Flow
Catalog #: FAB1429S
Flow
Catalog #: FAB1429V
Flow
Catalog #: FAB1429N
Flow
Catalog #: FAB1429U
Flow
Catalog #: FAB1429T
Flow
ICC/IF, WB

Recombinant Monoclonal Antibody

Catalog #: RDC0018
Catalog #: RDC0017
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