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5 results for "Calcium-Sensitive Protease Modulator Inhibitors" in Products

Calcium-Sensitive Protease Modulator Inhibitors Products

Calpain and cathepsin are calcium-sensitive proteases. Calpains are a family of 14 cysteine proteases that are involved in a range of cellular processes. These include remodeling of cytoskeletal attachments to the plasma membrane during cell fusion and cell motility, proteolytic modification of molecules in signal transduction pathways, degradation of enzymes controling progression through the cell cycle, regulation of gene expression, substrate degradation in some apoptotic pathways, and an ...

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Proteasome and calpain inhibitor. Inhibits NF-κB activation

Alternate Names: Z-LLL-al,Z-Leu-Leu-Leu-CHO
Chemical Name: N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-L-leucinamide
Purity: ≥95% (HPLC)
Proteasome and calpain inhibitor. Inhibits NF-κB activation

Selective cathepsin B inhibitor

Chemical Name: N-[[(2S,3S)-3-[(Propylamino)carbonyl]-2-oxiranyl]carbonyl]-L-isoleucyl-L-proline
Purity: ≥98% (HPLC)
Selective cathepsin B inhibitor

Cathepsin L inhibitor

Chemical Name: N-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophan-2-[[[2-[(2-ethylphenyl)amino]-2-oxoethyl]thio]carbonyl]hydrazide
Purity: ≥97% (HPLC)
Cathepsin L inhibitor

Cathepsin inhibitor; interferes with autolysosomal digestion

Chemical Name: (2S,3S)-3-[[[(1S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic acid ethyl ester
Purity: ≥98% (HPLC)
Cathepsin inhibitor; interferes with autolysosomal digestion

Potent cathepsin K inhibitor

Chemical Name: N-[1-[[(Cyanomethyl)amino]carbonyl]cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazolyl]benzamide
Purity: ≥98% (HPLC)
Potent cathepsin K inhibitor
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