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595 results for "kinase inhibitors" in Products
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595 results for "kinase inhibitors" in Products
A bioactive compound library of 160 kinase inhibitors (250 μL 10 mM DMSO solutions) for high-throughput screening, high-content screening and chemical biology applications
Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component
| Alternate Names : | y27632, Y-27632 2HCl, ROCK inhibitor, ROCK1 inhibitor |
| Chemical Name : | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
| Purity : | ≥98% (HPLC) |
Potent protein kinase A inhibitor
| Alternate Names : | Protein kinase inhibitor-(6-22)-amide, PKI-(6-22)-amide |
| Purity : | ≥95% (HPLC) |
Selective inhibitor of myosin light chain kinase
| Alternate Names : | Myosin Light Chain Kinase Inhibitor Peptide 18 |
| Purity : | ≥95% (HPLC) |
Catalog #:
5985
Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates
| Chemical Name : | 6-(2-Benzothiazolyl)-1-ethyl-2-[(1E)-2-(methylphenylamino)ethenyl]-3-phenyl-1H-benzimidazolium iodide |
| Purity : | ≥98% (HPLC) |
IRAK4 and IRAK1 inhibitor
| Chemical Name : | N-[1-[2-(4-Morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitrobenzamide |
| Purity : | ≥98% (HPLC) |
Selective FAK inhibitor
| Alternate Names : | Y15, NSC 677249 |
| Chemical Name : | 1,2,4,5-Benzenetetramine tetrahydrochloride |
Inhibits Lyn-dependent activities of IL-5 receptor; cell-permeable
Y-27632 synthesized to cGMP guidelines
| Chemical Name : | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
| Purity : | ≥99% |
Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
| Chemical Name : | 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
| Purity : | ≥99% (HPLC) |
Catalog #:
TB1614-GMP
SB 431542 synthesized to cGMP guidelines
| Chemical Name : | 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
| Purity : | ≥99% |
Highly selective GSK-3 inhibitor; acts as Wnt activator
| Alternate Names : | CHIR99021, CT99021 |
| Chemical Name : | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile |
| Purity : | ≥98% (HPLC) |
CHIR 99021 synthesized to cGMP guidelines
| Chemical Name : | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile |
| Purity : | ≥99% |
Selective inhibitor of TGF-βRI, ALK4 and ALK7
| Chemical Name : | 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide |
| Purity : | ≥98% (HPLC) |
Non-selective protein kinase inhibitor
| Alternate Names : | AM-2282 |
| Chemical Name : | [9S-(9α,10β,11β,13α)]-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one |
| Purity : | ≥98% (HPLC) |
Potent adenosine kinase inhibitor; also inhibits nucleoside transporters and a range of other kinases
| Chemical Name : | 5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
| Purity : | ≥90% (HPLC) |
Adenosine kinase inhibitor; orally active
| Chemical Name : | 5-(3-Bromophenyl)-7-[6-(4-morpholinyl)-3-pyrido[2,3-d]byrimidin-4-amine hydrochloride |
| Purity : | ≥98% (HPLC) |
EGFR-kinase inhibitor
| Alternate Names : | ZM 252868 |
| Chemical Name : | 4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline hydrochloride |
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
| Chemical Name : | 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride |
| Purity : | ≥99% (HPLC) |
High affinity and selective p38 kinase inhibitor
| Alternate Names : | Doramapimod |
| Chemical Name : | N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea |
| Purity : | ≥99% (HPLC) |
Potent and selective RIP3 kinase inhibitor
| Chemical Name : | N-5-Benzothiazolyl-6-[(1-methylethyl)sulfonyl]-4-quinolinamine |
| Purity : | ≥98% (HPLC) |
Integrated stress response (ISR) inhibitor
| Chemical Name : | N,N'-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] |
| Purity : | ≥99% (HPLC) |
Selective CaM kinase kinase inhibitor
| Chemical Name : | 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate |
| Purity : | ≥98% (HPLC) |
Selective inhibitor of p38 MAPK
| Chemical Name : | 4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine |
| Purity : | ≥98% (HPLC) |
mTOR inhibitor; immunosuppressant
| Chemical Name : | (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone |
| Purity : | ≥98% (HPLC) |
