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90 results for "Degrader Building Blocks" in Products

90 results for "Degrader Building Blocks" in Products

Functionalized VHL ligand for PROTACs

Chemical Name : (4R)-3-Methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide dihydrochloride
Purity : ≥98% (HPLC)
Ubiquitin Ligase (E3) Inhibitors Small Molecule
Catalog #: 6627

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names : Thalidomide - linker 4
Chemical Name : 4-[(6-Aminohexyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
Purity : ≥95% (HPLC)
Degrader Building Blocks Small Molecule
Catalog #: 6471

Functionalized IAP ligand for PROTACs

Chemical Name : tert-Butyl [(S)-1-[[(S)-2-[(2S,4S)-4-amino-2-[[(R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]amino]-1-oxopropan-2-yl](methyl)carbamate hydrochloride
Purity : ≥98% (HPLC)
Degrader Building Blocks Small Molecule
Catalog #: 6952

Hydroxyl functionalized VHL ligand

Chemical Name : (2S,4R)-1-((S)-2-(1-Fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity : ≥98% (HPLC)
Degrader Building Blocks Small Molecule

Negative control for VH 032, amine (Cat. No. 6462)

Chemical Name : (2S,4S)-1-[(2S)-2-Amino-3,3-dimethyl-butanoyl]-4-hydroxy-N-[[4-(4-methylthiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide dihydrochloride
Purity : ≥98% (HPLC)
Degrader Building Blocks Small Molecule
Catalog #: 6917

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names : Thalidomide - linker 9
Chemical Name : 4-(4-Aminobutoxy)-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
Purity : ≥95% (HPLC)
Degrader Building Blocks Small Molecule
Catalog #: 6637

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Alternate Names : Pomalidomide - linker 1
Chemical Name : 4-[[2-[2-(2-Aminoethoxy)ethoxy]ethyl]amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
Purity : ≥95% (HPLC)
Degrader Building Blocks Small Molecule
Catalog #: 6679

VHL ligand with PEG linker and terminal acid for onward chemistry

Alternate Names : VH 032 - linker 4
Chemical Name : (S)-15-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-16,16-dimethyl-13-oxo-4,7,10-trioxa-14-azaheptadecanoic acid
Purity : ≥95% (HPLC)
Degrader Building Blocks Small Molecule
Catalog #: 6686

Cereblon ligand with PEG linker and terminal alkyne for onward chemistry

Alternate Names : Thalidomide - linker 5
Chemical Name : 2-(2,6-Dioxo-3-piperidinyl)-4-[2-[2-(2-propyn-1-yloxy)oxy]ethoxy]-1H-isoindole-1,3(2H)dione
Purity : ≥95% (HPLC)
Degrader Building Blocks Small Molecule
Catalog #: 6468

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Alternate Names : Thalidomide - linker 2
Chemical Name : N-(14-Amino-3,6,9,12-tetraoxatetradec-1-yl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide hydrochloride
Purity : ≥95% (HPLC)
Degrader Building Blocks Small Molecule
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