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Thank you for your interest in our Current and Emerging Immune Checkpoint Targets for Immuno-Oncology Research eBook.

You will receive an email with a link to download the eBook shortly.

Current and Emerging Immune Checkpoint Targets for Immuno-Oncology Research eBook

In this eBook, you’ll find information about:

  • Different B7 family proteins and their effects on immune cell activation
  • Members of the butyrophilin family of T cell co-stimulatory/co-inhibitory molecules
  • How tumor cells can exploit the CD47-SIRP alpha myeloid cell-specific immune checkpoint pathway to evade phagocytic destruction
  • The effects of IDO/TDO and the kynurenine pathway on immune cell functions
  • Different LAG-3 and TIM-3 ligands and how these ligand-receptor interactions can negatively regulate anti-tumor immune responses
  • The immunosuppressive effects of the LILRB family
  • The potential of CD96, PVRIG, TIGIT, and other VSTM and VSIG family proteins as next generation immuno-oncology targets
  • Co-stimulatory members of the TNF receptor superfamily and their immunotherapeutic potential

Please also explore these additional immuno-oncology-related resources that we offer:

A Look Inside a Tumor: Mechanisms of Tumor Evasion and Immunosuppression in the Tumor Microenvironment poster

Webinar: Emerging Targets for Cancer Immunotherapy Research

Immunotherapy: Purified Proteins for Immunotherapy Research and Clinical Manufacturing

T Cell Co-Signaling Pathway: Ligand-Receptor Interactions

Blog: Targeting Myeloid-derived Suppressor Cells for Cancer Immunotherapy

Immune Cell Markers Interactive Resource Tool