Innovative and High Performance Neuroscience Reagents
Neurotransmission, or synaptic transmission, involves the passage of signals from one neuron to another. Synaptic communication, and the action potentials on which it is dependent, are integral for all informational processing capabilities of the brain. Bio-Techne offers a unique collection of Tocris small molecules for neurotransmission research, including research standards and exciting new chemical tools.
As the host defense mechanism of the central nervous system (CNS), neuroinflammation protects normal brain function and structure in response to injury and infection. Neuroinflammatory processes may be beneficial, leading to the clearance of unwanted material and dying cells in healthy brain development, but also pathogenic, causing neuronal cell death and the production of antibodies against CNS proteins. Neuroinflammation is a key pathogenic feature of many neurodegenerative diseases.
Neuropeptides integrate with peptide hormones to regulate diverse physiological processes, including feeding and appetite, cardiovascular function and circadian rhythms. The Tocris® range of reagents includes small molecules and peptides for the investigation of neuroendocrinology pathways.
The clinical application of stem cells in neuroscience, particularly in neurodegenerative diseases, is an expanding area of research. Small molecules offer advantages over traditional reprogramming and differentiation methods, enabling fast production of a large number of cells.