W-9 hydrochloride

Name: W-9 hydrochloride
Brand: tocris
SKU: 0370

Catalog # 0370

Datasheet / COA / SDS

Order Information

Bio-Techne Corporation

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Shipping Information

$35 to United States

Products in stock will be shipped in 1-3 business days unless specified.

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Key Product Details

Description:	Calmodulin antagonist
Chemical Name:	N-(6-Aminohexyl)-5-chloro-2-naphthalenesulfonamide hydrochloride
Molecular Weight:	377.33

View Full Technical Details for W-9 hydrochloride

Technical Data
Citations / Reviews

Biological Activity

W-9 hydrochloride is a calmodulin antagonist (inhibits calmodulin-activated PDE activity with an IC₅₀ of 72 μM).

Technical Data

M. Wt	377.33
Formula	C₁₆H₂₁ClN₂O₂S.HCl
Storage	Store at RT
CAS Number	69762-85-2
PubChem ID	2735339
InChi Key	FGWDLQXTCSKXSK-UHFFFAOYSA-N
Smiles	Cl.NCCCCCCNS(=O)(=O)C1=CC=C2C(Cl)=CC=CC2=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	ethanol		25

Preparing Stock Solutions

The following data is based on the product molecular weight 377.33.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	10.60 mL	53.00 mL	106.01 mL
1.25 mM	2.12 mL	10.60 mL	21.20 mL
2.5 mM	1.06 mL	5.30 mL	10.60 mL
12.5 mM	0.21 mL	1.06 mL	2.12 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Hidaka Selective inhibitors of Ca²⁺-binding modulator of phosphodiesterase produce vascular relaxation and inhibit actin-myosin interaction. Mol.Pharmacol. 1979 PMID: 218093
Hidaka N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. Proc.Natl.Acad.Sci.U.S.A. 1981 PMID: 6945588